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Articles ( Showing 121-140 of 132 items)
Searched for: [ Keywords: "China" ] clear all
Journal Article
Five Common Finance and Accounting Problems of Start-Up Companies
by Derrald Stice , Earl K. Stice  and  James D. Stice
Abstract
You have a product or service for which the world has been waiting. You've scraped together enough cash to get your idea off the ground. You are confident that your business will succeed. And yet, it is often the case that a short time later you are out of business. Numbers from the U.S. Bureau of Labor Statistics indicate that about half of new businesses fail within the first [...] Read more
Hit Affiliation:
HKU Business School, University of Hong Kong, Hong Kong, China

Letter
Analysis of the Mediating Effect of Economic Policy Uncertainty Affecting Commercial Bank Credit
by Juan Meng  and  Zhe Zhou
Abstract
We analyze the annual microdata of China's 100 commercial banks from 2007 to 2018 using the mediating effect analysis method, analyze the negative impact of economic policy uncertainty on the credit scale of commercial banks, and then verify the intermediary effects of the operational risks and short-term capital liquidity of commercial banks in the impact of economic policy un [...] Read more
Hit Affiliation:
Business School, Hunan First Normal University, Changsha, China

Review
E3 ubiquitin ligase-dependent regulatory mechanism of TRIM family in carcinogenesis
by Gui Zhang , Yunfang Zhang , Luxuan Chen , Langxia Liu  and  Xuejuan Gao
Abstract
Tripartite motif-containing (TRIM) proteins consist of over 80 proteins, the majority of which exhibit E3 ubiquitin ligase activity. E3 ligases have a critical role in various cellular processes by specifically recognizing and ubiquitinating substrate proteins to promote their proteasomal degradation or alter their activities. Numerous studies have indicated that TRIMs are invo [...] Read more
Hit Affiliation:
MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Department of Nephrology, Affiliated Huadu Hospital, Southern Medical University (People's Hospital of Huadu District), Guangzhou, China.

Letter
Time to build, financial frictions, and the effectiveness of fiscal stimulus
by Zhiming Ao , Ziyue Chen  and  He Nie
Abstract
By introducing time to build, which creates a time-lag between government investment and the accumulation of productive capital, into an analysis of fiscal stimulus to the economy with financial frictions, we find that the effectiveness of fiscal policy is dampened. While the weakening effects of time to build become significantly weaker alongside with a higher fraction of gove [...] Read more
Hit Affiliation:
School of Economics, Jinan University, Guangzhou, China

Review
A comprehensive review on biogenically synthesized inorganic nanoparticles and their applications in anticancer activities
by Zahra Barreto , Areej Fatima , Tuba Tariq , Ayesha Zafar , Muhammad Saqib Saif , Amina Zafar , Areeba Yousaf , Huang Xue  and  Murtaza Hasan
Abstract
The progression in nanotechnology has revolutionized the biomedical sciences for diagnosis and treatment of diseases like cancer. There have been many kinds of nanomaterials but Inorganic nanomaterials have been considered potential candidates for anticancer activities due to their high biocompatibility, less toxicity, high stability, and high precision in targeting affected ce [...] Read more
Hit Affiliation:
Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing 100871, China
College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Journal Article
Portfolio Allocation with Medical Expenditure Risk-A Life Cycle Model and Machine Learning Analysis
by You Du  and  Weige Huang
Abstract
This paper explores how the medical expenditure risk affects the households’ portfolio choice across health status theoretically in a life cycle model and empirically using machine learning methods. Medical expenditure risk, as a background risk, has the potential to influence households’ financial decisions. A higher medical expenditure risk leads to a larger fluct [...] Read more
Hit Affiliation:
Faculty of Economics, Shenzhen MSU-BIT University, Shenzhen, China

Journal Article
Forecasting Parameters in the SABR Model
by Li Chen , Jianing Zhu  and  Cunyi Yang
Abstract
We present two approaches to forecasting parameters in the SABR model. The first approach is the vector autoregressive moving-average model (VARMA) for the time series of the in-sample calibrated parameters, and the second is based on machine learning techniques called epsilon-support vector regression (ε-SVR). Using daily data of S&P 500 ETF option prices from Janu [...] Read more
Hit Affiliation:
Lingnan College, Sun Yat-Sen University, Guangzhou, China

Review
Repurposing anti-parasite benzimidazole drugs as selective anti-cancer chemotherapeutics
by Fatemeh Movahedi , Li Li  and  Zhi Ping Xu
Abstract
Cancer chemotherapy is generally associated with many severe adverse effects. Many cancer studies are currently focused on repurposing conventional non-toxic anti-parasite drugs for cancer treatment. Since cancer cells and parasites have many features in common, some anti-parasite drugs such as benzimidazoles have been recently found to possess the anti-cancer activity. Benzimi [...] Read more
Hit Affiliation:
Institute of Biomedical Health Technology and Engineering and Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen 518107, China

Review
Liver fibrosis from viral hepatitis: advances in non-invasive diagnosis
by Jincheng Wang , Jinyu Sun , Tao Qin , Xiaohan Ren , Jin Zhang  and  Xiaojie Lu
Abstract
The stages of liver fibrosis can reflect the severity of chronic viral hepatitis and the probability of liver cancer. Biopsy is still regarded as the reference for staging fibrosis, but the invasive method is not suitable for first-line screening. In recent years, noninvasive methods for detecting virus-driven liver fibrosis have been developed rapidly, which mainly include bio [...] Read more
Hit Affiliation:
Department of General Surgery, Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University,Nanjing, Jiangsu, China

Journal Article
LTBP1 promotes the progression of triple negative breast cancer via activating the RhoA/ROCK signaling pathway
by Jingcheng Zhang , Hong Deng  and  Jun Wang
Abstract
The latent transforming growth factor-beta (TGF-β) binding protein 1 (LTBP1) has been implicated in various cellular processes, but its role in triple-negative breast cancer (TNBC) remains unclear. In this study, we investigated the impact of LTBP1 on TNBC progression and its underlying mechanisms. Analysis of online datasets revealed elevated LTBP1 mRNA expression in brea [...] Read more
Hit Affiliation:
Department of General Surgery, The Affiliated Hospital of Southwest Medical University, Sichuan, China

Review
Advances in the Use of Nanomaterials in Tumour Therapy: Challenges and Prospects
by Hongmei Yang , Chen Li  and  Qiang Xie
Abstract
Nanomaterials have shown great potential in anti-tumor applications and are currently the focus of research. This review article aims to provide a comprehensive overview of the challenges encountered in oncology treatment and how nanomaterials are being utilized to overcome these obstacles. The authors discuss the limitations of conventional treatments, including limited effica [...] Read more
Hit Affiliation:
Department of Vascular Interventional Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong 510630, China.

Review
Application of nanodrugs in the treatment of cardiovascular diseases
by Qiang Xie , Hongmei Yang  and  Wenjie Shi
Abstract
Cardiovascular disease is still a disease with high incidence rate and mortality. Although advanced technology continues to increase our understanding of cardiovascular disease, its diagnosis and treatment still have limitations. As an emerging interdisciplinary method, nanotechnology has shown enormous clinical application potential. Nanomaterials have unique physical and chem [...] Read more
Hit Affiliation:
Department of Vascular Interventional Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, Guangdong, China, 510630