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Open Access Journal Article
Detection of 16 kDa Protein from Mycobacterium Tuberculosis Using Interdigitated Electrode
by S.S. Rani  and  Subash C.B. Gopinath
Abstract
 In the past, researchers investigated the immune response acting against mycobacterial antigens in tuberculosis (TB). Several ELISA tests have been conducted for the diagnosis of tuberculosis. Other researchers manipulated 16 kDa antigen from Mycobacterium Tuberculosis to develop a tuberculosis diagnostic test while some others studied the subspecies of M. [...] Read more

Open Access Journal Article
Polymers containing natural plant phenolic compounds for peripheral nerve injury
by Tong Zheng , Shuoke Qiu , Lei Li , Binglong Li  and  Meng Zhang
Abstract
Peripheral nerve injury is a serious and disabling disease prevalent in the world. It caused by trauma is often accompanied with soft tissue injuries, fractures, infections, etc., and can cause permanent damage. The treatment methods of peripheral nerve injury mainly include traditional microsurgical repair, neurotrophic drug treatment, as well as cuttingedge nerve conduit trea [...] Read more

Open Access Journal Article
Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics
by Siyu Liu
Abstract
Noninvasive acquisition of deep tissue temperature has important applications in home health monitoring, hyperthermia safety control, and other domains. In this work, we present here a novel magnetically mediated thermoacoustic temperature measurement method. Utilizing coil to stimulate amplitude modulated magnetic field and ultrasound transducer to receive the generated thermo [...] Read more

Open Access Journal Article
Advances in Novel Tumor Therapeutics Based on Nanomaterial Technologies
by Chen Li  and  Yi Liu
Abstract
Cancer is the leading cause of death in the world, throughout the global researches of cancer treatment, people have a deeper understanding of cancer, and the treatment methods are constantly breakthrough. Conventional surgery, chemotherapy and radiotherapy have serious adverse effects and patients' quality of life is not significantly improved. Now, photodynamic therapy, p [...] Read more

Open Access Review
Overcoming the challenge: cell-penetrating peptides and membrane permeability
by Yuan Gu , Long Wu , Yasir Hameed  and  Mohsen Nabi-Afjadi
Abstract
Cell-penetrating peptides (CPPs) have emerged as a promising strategy for enhancing the membrane permeability of bioactive molecules, particularly in the treatment of central nervous system diseases. CPPs possess the ability to deliver a diverse array of bioactive molecules into cells using either covalent or non-covalent approaches, with a preference for non-covalent methods t [...] Read more

Open Access Review
Application of nanodrugs in the treatment of cardiovascular diseases
by Qiang Xie , Hongmei Yang  and  Wenjie Shi
Abstract
Cardiovascular disease is still a disease with high incidence rate and mortality. Although advanced technology continues to increase our understanding of cardiovascular disease, its diagnosis and treatment still have limitations. As an emerging interdisciplinary method, nanotechnology has shown enormous clinical application potential. Nanomaterials have unique physical and chem [...] Read more

Open Access Review
A comprehensive review on biogenically synthesized inorganic nanoparticles and their applications in anticancer activities
by Zahra Barreto , Areej Fatima , Tuba Tariq , Ayesha Zafar , Muhammad Saqib Saif , Amina Zafar , Areeba Yousaf , Huang Xue  and  Murtaza Hasan
Abstract
The progression in nanotechnology has revolutionized the biomedical sciences for diagnosis and treatment of diseases like cancer. There have been many kinds of nanomaterials but Inorganic nanomaterials have been considered potential candidates for anticancer activities due to their high biocompatibility, less toxicity, high stability, and high precision in targeting affected ce [...] Read more

Open Access Review
Advances in the use of cell-membrane encapsulated nanoparticles to target tumor drugs
by Mengdie Feng  and  Yonghua Zheng
Abstract
Cancer treatment faces multiple challenges, including tumor heterogeneity, drug resistance, microenvironment influence, treatment side effects, and treatment cost. The heterogeneity of the tumor makes the effect of the same treatment vary in different patients, so the development of personalized treatment strategies is crucial. In addition, resistance of tumor cells to therapeu [...] Read more

Open Access Review
Advances in rapid detection of Pseudomonas aeruginosa with DNase-based sensors
by Shriya Madan  and  Yongzhi Chen
Abstract
Pseudomonas aeruginosa is a common pathogen, and its presence in medical environments and water bodies has attracted widespread attention. Traditional detection methods are usually time-consuming and cumbersome, so it is necessary to develop a rapid and sensitive detection technology. DNase can specifically recognize and cut DNA molecules complementary to its substrate sequence [...] Read more