Noninvasive acquisition of deep tissue temperature has important applications in home health monitoring, hyperthermia safety control, and other domains. In this work, we present here a novel magnetically mediated thermoacoustic temperature measurement method. Utilizing coil to stimulate amplitude modulated magnetic field and ultrasound transducer to receive the generated thermoacoustic wave from the inserted magnetic nanoparticles. Benefiting from the high sensitivity of thermoacoustic emission from nanoparticles and the deep penetration capability of both magnetic field and ultrasound propagation, the proposed thermoacoustic temperature measurement system enables a high measurement accuracy of 0.5 degrees Celsius in real time. This work potentially facilitates further development of closed loop magnetic hyperthermia for practical clinical applications.
National Natural Science Foundation of China (12204242)
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Natural Science Foundation of Jiangsu Province (BK20210323)
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Liu, S. Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors, 2022, 1, 5. https://doi.org/10.58567/bab01010005
AMA Style
Liu S. Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors; 2022, 1(1):5. https://doi.org/10.58567/bab01010005
Chicago/Turabian Style
Liu, Siyu 2022. "Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics" Biomaterials and Biosensors 1, no.1:5. https://doi.org/10.58567/bab01010005
APA style
Liu, S. (2022). Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors, 1(1), 5. https://doi.org/10.58567/bab01010005
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References
Pouch M. A., Theodore W. C., Susan M. S., and Chandra M. S.. “In Vivo Noninvasive Temperature Measurement by B-Mode Ultrasound Imaging.” Journal of Ultrasound in Medicine 29, no. 11 (2010): 1595–1606. https://doi.org/10.7863/jum.2010.29.11.1595.
Guo, Shoujing, Shuwen Wei, Soohyun Lee, Mary Sheu, Sewon Kang, and Jin U. Kang. “Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring during Cutaneous Laser Therapy.” IEEE Journal of Translational Engineering in Health and Medicine 7 (2019): 1–8. https://doi.org/10.1109/jtehm.2019.2943317.
Pramanik Manojit, and Lihong V. Wang. “Thermoacoustic and Photoacoustic Sensing of Temperature.” Journal of Biomedical Optics 14, no. 5 (2009): 054024. https://doi.org/10.1117/1.3247155.
Liu Siyu, Xiaohua Feng, Haoran Jin, Ruochong Zhang, Yunqi Luo, Zesheng Zheng, Fei Gao, and Yuanjin Zheng. “Handheld Photoacoustic Imager for Theranostics in 3D.” IEEE Transactions on Medical Imaging 38, no. 9 (2019): 2037–46. https://doi.org/10.1109/tmi.2019.2900656.
Yao Junjie, Haixin Ke, Stephen Tai, Yong Zhou, and Lihong V. Wang. “Absolute Photoacoustic Thermometry in Deep Tissue.” Optics Letters 38, no. 24 (2013): 5228. https://doi.org/10.1364/ol.38.005228.
Liu Siyu, Weitao Song, Xinqin Liao, Tony Tae-Hyoung Kim, and Yuanjin Zheng. “Development of a Handheld Volumetric Photoacoustic Imaging System with a Central-Holed 2D Matrix Aperture.” IEEE Transactions on Biomedical Engineering 67, no. 9 (2020): 2482–89. https://doi.org/10.1109/tbme.2019.2963464.
Liu Siyu, Ruochong Zhang, Zesheng Zheng, and Yuanjin Zheng. “Electromagnetic–Acoustic Sensing for Biomedical Applications.” Sensors 18, no. 10 (2018): 3203. https://doi.org/10.3390/s18103203.
Liu Siyu, Xiaohua Feng, Zhang Ruochong, and Yuanjin Zheng. “Portable Photoacoustic System for Noninvasive Blood Temperature Measurement.” 2018 IEEE International Symposium on Circuits and Systems (ISCAS), 2018. https://doi.org/10.1109/iscas.2018.8351607.
Liu Siyu, Ruochong Zhang, Yunqi Luo, and Yuanjin Zheng. “Magnetoacoustic Microscopic Imaging of Conductive Objects and Nanoparticles Distribution.” Journal of Applied Physics 122, no. 12 (2017): 124502. https://doi.org/10.1063/1.5003920.
