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Articles ( Showing 1-20 of 12 items)
Searched for: [ Keywords: "IL-8" ] clear all
Journal Article
Effect of interleukin-8 on docetaxel resistance in prostate cancer cells: insights into the role of multidrug resistance 1 protein modulation
by Suleyman ILHAN
Abstract
Although docetaxel treatment yields a high survival rate for prostate cancer (PCa), resistance eventually develops in many patients. Understanding the underlying mechanisms of docetaxel resistance is essential for improving treatment strategies. Cytokines, which play a role in cell signaling and immune responses, have been implicated in drug resistance mechanisms. The study rev [...] Read more

Journal Article
Mechanism of congenital lymphocytes and intestinal immunity regulated by gut microbial metabolites via metabolite-sensing receptor Ffar2
by Chen Deng
Abstract
Objective: The DSS was utilized to construct colitis model of mouse. The colitis mice were colonized with gut microbiota. The effects of gut microbial metabolites on colitis were studied. The mechanisms of gut microbial metabolites to improve intestinal immunity were also further explored. Methods: The male BALB/c mice were selected to construct colitis mouse model with DSS and [...] Read more

Journal Article
Effects of Horizontal Mergers on Prices of Generic Drugs
by Antonio J. Trujillo , Mariana Socal  and  Gerard Anderson
Abstract
This paper quantifies the impact of horizontal mergers on the prices of drugs. We study all mergers between two publicly traded pharmaceutical companies working in the US between 2010 and 2015 and their effect on their drugs prices. Using a differences-in-differences approach, we estimate that drugs marketed by the merging firms experience an AWP increase of about between 8% an [...] Read more

Journal Article
Impact of Institutional Quality and Research and Development (R&D) on Agricultural Productivity in Low-and Middle-Income Countries
by Agossou Justin Tovilode  and  Wanki Moon
Abstract
This study investigates the impact of institutions and public agricultural Research and Development (R&D) on agricultural productivity in low- and middle-income countries. The paper employs panel data with fixed-effects models, spanning 12 years and including 49 low-and middle-income countries. Agricultural productivity is measured by cereal yield, while institutional facto [...] Read more
Hit Affiliation:
Agribusiness Economics, Southern Illinois University of Carbondale, Carbondale, IL, USA

Journal Article
How Does FDI-Led Growth Strategy Work? Some Lessons from China for Developing Countries
by Kevin H. Zhang
Abstract
Foreign direct investment (FDI) is widely viewed as a key driving force behind China’s exceptional growth performance in the last four decades. This paper investigates several questions posed by China’s success in capturing gains from FDI. What explains that success? Can other countries replicate it, or is it unique to China? What lessons are from China for other co [...] Read more
Hit Affiliation:
Department of Economics, Illinois State University Normal, IL 61790-4200, US

Journal Article
Optimizing Business Strategy through SWOT and QSPM: A Case Study of CV Cita Nasional’s Strategic Challenges
by Dori Susadi Wahmil , Susatyo Nugroho Widyo Pramono  and  M. Mujiya Ulkhaq
Abstract
The fast-paced evolution of the business world today requires business players to work diligently to maintain their competitive advantage. To enhance a company's competitive edge, strategic business planning is essential. A well-developed business strategy allows a company to achieve the best market position, improve sales performance, and define approaches to gain a competitiv [...] Read more

Journal Article
Credit risk and Tunisian bank stability in the Covid-19 wave
by Emna Trabelsi  and  Malek Ben Mansour
Abstract
Banks are at the core of economic functioning in various countries and are the cause of their development in various fields. In a changing environment, they must deal with certain risks and maintain financial stability as the ultimate objective. The primary objective of this study is to examine the correlation between credit risk and bank stability within the Tunisian banking s [...] Read more

Journal Article
Do Dirty Energies Influence Sustainable Energy Indices Price Formation?
by Rui Dias  and  Rosa Galvão
Abstract
The clean energy revolution is a global concern. Cross-border collaboration is crucial for sharing knowledge, pooling resources, and tackling complex challenges on a global scale. International partnerships can accelerate innovation by drawing on diverse knowledge and experience from different regions. Access to capital is a key driver of innovation and entrepreneurship in clea [...] Read more

Journal Article
Beyond Their Borders – Economic Freedom: Uncovering One of the Motivations of Unauthorized Migration to the U.S.A.
by Rafael Acevedo  and  Juan Bogado
Abstract
This study documents the relationship between economic freedom and unauthorized immigration to the U.S.A. and tries to answer a still-in-debate question, what motivates people to unauthorizedly migrate? Using the generated instrument variables methodology, and a data panel of 15 countries and 16 years, the endogenous variable is the gap in economic freedom between the country o [...] Read more
Hit Affiliation:
Department of Accounting, Economics, and Finance, University of Illinois Springfield, Springfield, IL, USA

Journal Article
Entrepreneurship: The Driving Force for Economic Growth in the Twenty-First Century in the European Union
by Rafael Acevedo  and  Maria Lorca-Susino
Abstract
Economic growth rests on entrepreneurship and capitalism. Entrepreneurship is important because entrepreneurs work unceasingly to create, use, and disseminate new products and productive techniques to raise living standards. Capitalism is characterized by private property rights, a free market, and the pursuit of profit, which are driving forces for innovation and productivity [...] Read more
Hit Affiliation:
Department of Accounting, Economics, and Finance, University of Illinois, Springfield, IL, USA

Journal Article
USA – Innovation Index: A State - Level Proposal
by Rafael Acevedo , Jose U. Mora  and  Jorge Romero-Habeych
Abstract
We propose an open-access innovation index for the U.S. states. This index was built by classifying into four core areas the twelve more important indicators, inputs, and outputs, that are widely accepted in the literature as the most relevant for measuring innovation. We consider the indicators aggregated in the areas of human capital and business environment as the inputs tha [...] Read more
Hit Affiliation:
Department of Accounting, Economics, and Finance, University of Illinois, Springfield, IL, USA

Review
Role of macrophage polarization in cancer progression and their association with COVID-19 severity
by Abhimanyu Thakur , Rumpa Banerjee , Sudha Thakur , Gaurav Kumar  and  Shyam Sundar Thakur
Abstract
Macrophages are a type of white blood cells that can exist in two different functional states, known as M1 and M2. M1 macrophages secrete pro-inflammatory cytokines that can promote tumor growth and metastasis, whereas M2 macrophages secrete anti-inflammatory cytokines that can inhibit tumor progression. This phenomenon, referred to as macrophage polarization, has been implicat [...] Read more
Hit Affiliation:
Ben May Department for Cancer Research, Pritzker School of Molecular Engineering, University of Chicago, IL, USA.