Open Access Journal Article

How Does Lncrna Regulation Impact Cancer Metastasis

by Abreto Devit Mancheng a  and  Ugwemubwem Ossas a,*
a
Internal Medicine, Hopital du Mali, Bamako, Mali.
*
Author to whom correspondence should be addressed.
CI  2022, 6; 1(1), 6; https://doi.org/10.58567/ci01010002
Received: 19 May 2022 / Accepted: 7 June 2022 / Published Online: 14 June 2022
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Abstract

Metastasis is the major cause of cancer-related mortality. Metastasis is a process through which cancer spreads from its initial location to other sections of the body. Cancer cells' epithelial-mesenchymal transition (EMT), anoikis resistance, cell migration, and angiogenesis are all well-known steps in this process. Investigating the molecular processes that govern cancer metastatic progression may lead to more effective diagnostic and treatment strategies. Long non-coding RNAs (lncRNAs) have recently discovered to have a vital more than 200 nucleotides. A rising body of research indicates that lncRNAs have a role in a wide range of biological processes and diseases, including cancer. The usage of LncRNA in cancer metastasis has been widely researched. However, according to current studies, lncRNA is mostly associated with the EMT process. This review focuses on the processes behind lncRNA involvement in cancer metastasis.

Keywords: Noncoding RNAs (ncRNAs); Long noncoding RNAs (lncRNAs); Cancer metastasis; Gene regulation;
Copyright: © 2022 by Mancheng and Ossas. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.