Noninvasive acquisition of deep tissue temperature has important applications in home health monitoring, hyperthermia safety control, and other domains. In this work, we present here a novel magnetically mediated thermoacoustic temperature measurement method. Utilizing coil to stimulate amplitude modulated magnetic field and ultrasound transducer to receive the generated thermoacoustic wave from the inserted magnetic nanoparticles. Benefiting from the high sensitivity of thermoacoustic emission from nanoparticles and the deep penetration capability of both magnetic field and ultrasound propagation, the proposed thermoacoustic temperature measurement system enables a high measurement accuracy of 0.5 degrees Celsius in real time. This work potentially facilitates further development of closed loop magnetic hyperthermia for practical clinical applications.
National Natural Science Foundation of China (12204242)
Natural Science Foundation of Jiangsu Province (BK20210323)
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Liu, S. Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors, 2022, 1, 5. https://doi.org/10.58567/bab01010005
Liu S. Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors; 2022, 1(1):5. https://doi.org/10.58567/bab01010005
Liu, Siyu 2022. "Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics" Biomaterials and Biosensors 1, no.1: 5. https://doi.org/10.58567/bab01010005
Liu, S. (2022). Noninvasive Deep-Tissue Temperature Monitoring Based on Magnetic Mediated Thermoacoustics. Biomaterials and Biosensors, 1(1), 5. https://doi.org/10.58567/bab01010005
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